Final Issue of the Fantastic Four?

Could this be it?  After years of publication, could Marvel's First Family finally be done? 

Well, yes and no.  One of the original four will die (supposedly), and you can't have the Fantastic Three I suppose.  Even if they've used that concept several times already.  Although the team might disband temporarily, don't expect their adventures to end altogether.  Between cleaning up various plot threads and dealing with the emotional aftermath of a death, there's still alot more room for stories.  The book may be coming to a close, but the legacy of the Fantastic for is far from over.